About Pergonal:

Common Uses: This medicine is given as an injection for a number of days prior to an injection of human chorionic gonadotropin (hCG) to treat female infertility. It may also be used along with hCG to increase sperm production in men.

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Additional Information:

Generic Name: E: MENOTROPINS (men-oh-TROE-pins)

How to use this Medicine: Follow the directions for using this medicine provided by your doctor. This medicine is given as an injection. IF YOU ARE USING THIS MEDICINE AT HOME, a healthcare professional will provide detailed instructions for its appropriate use. Ask your doctor, nurse, or pharmacist any questions that you may have about this medicine or giving injections. TO USE THIS MEDICINE, draw up the diluent into a syringe. Add the diluent to the powder by slowly pushing in the plunger of the syringe. Mix the solution by rotating the container. Do not shake. The solution should be clear and free of particles. Draw up the solution for injection. Use a different syringe for this or switch needles just prior to injection. Needles with higher gauge (25G and higher) are smaller and less painful to the patient. Be sure all air bubbles are tapped out of the syringe. Wipe the injection site with an alcohol swab, then insert the syringe through the skin at the appropriate injection site (usually the upper thigh or buttocks). While holding the syringe in place, pull back on the plunger of the syringe to be sure that the needle is not in a vein. If the syringe begins to fill with blood, the needle is in a vein. If this happens, remove the needle from the skin, throw the syringe away, and start the procedure again using new materials (drug, syringes, etc.). AFTER GIVING THE INJECTION, cover the injection site with a small bandage if necessary. STORE THIS MEDICINE as directed on the prescription label. Protect from light. IF YOU MISS A DOSE OF THIS MEDICINE, contact your doctor for instructions.

Cautions: KEEP ALL DOCTOR AND LABORATORY appointments while you are using this medicine. DO NOT DRIVE, OPERATE MACHINERY, OR DO ANYTHING ELSE THAT COULD BE DANGEROUS until you know how you react to this medicine. Using this medicine alone, with other medicines, or with alcohol may lessen your ability to drive or to perform other potentially dangerous tasks. IF YOU EXPERIENCE difficulty breathing; tightness of chest; swelling of eyelids, face, or lips; or if you develop a rash or hives, tell your doctor immediately. Do not take any more doses of this medicine unless your doctor tells you to do so. FOR WOMEN: USING THIS MEDICINE may result in multiple pregnancy (twins, etc.). Discuss this possibility with your doctor. DO NOT USE THIS MEDICINE if you are or become pregnant. IF YOU SUSPECT THAT YOU COULD BE PREGNANT, contact your doctor. IT IS UNKNOWN IF THIS MEDICINE IS EXCRETED in breast milk. IF YOU ARE OR WILL BE BREAST-FEEDING while you are using this medicine, check with your doctor or pharmacist to discuss the risks to your baby.

Possible Side Effects: FOR WOMEN: SIDE EFFECTS, that may go away during treatment, include abdominal pain; fever; chills; muscle or joint pain; skin rash; pain or rash at the injection site; or dizziness. If they continue or are bothersome, check with your doctor. FOR MEN: A SIDE EFFECT, that may go away during treatment, is breast enlargement. If it continues or is bothersome, check with your doctor. CHECK WITH YOUR DOCTOR AS SOON AS POSSIBLE if you experience severe abdominal pain, abdominal bloating, nausea, vomiting, weight gain, sudden leg pain, severe headache, weakness, or shortness of breath. If you notice other effects not listed above, contact your doctor, nurse, or pharmacist.

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Dosage and amounts subject to availability:
75mg 1 injection

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FDA Warns on Black-Market IUDs : WASHINGTON -- Many intrauterine devices (IUDs) sold over the Internet from foreign pharmacies are not approved in the U.S. and are possibly dangerous, the FDA said. The agency said an investigation disclosed that patients in Rhode Island, Massachusetts, and Kentucky had received unapproved IUDs from healthcare providers who had bought them from foreign pharmacies, presumably to save money. In a "Dear Colleague" letter to providers, the FDA said it had uncovered distribution of "unapproved versions of FDA-approved products such as Mirena, Implanon, Copper-T, and ParaGard; as well as products not approved for use in the U.S., such as T-Safe." These products may not be as effective or safe as FDA-approved IUDs, the agency warned. Women who believe they may have received an unapproved IUD should use another contraceptive method and talk to their healthcare providers, the FDA recommended. The FDA also advised physicians to use extra caution when asked to insert IUDs provided by patients. Healthcare providers should verify that products are authentic FDA-approved devices and were purchased from a licensed U.S.-based supplier. The agency also noted that billing Medicaid or private insurers for unapproved medical products could bring criminal fraud charges. "To reduce the chance of receiving an unapproved or adulterated medical product, your Internet purchases should be made from state-licensed distributors or pharmacies located in the U.S.," the FDA said. It recommended buying only from Internet pharmacies displaying a logo from the National Association of Boards of Pharmacy, known as the VIPPS seal for Verified Internet Pharmacy Practice Sites. "Healthcare providers should be aware that purchasing medical products from websites that are outside of the U.S. may be illegal and may increase the risk of receiving a potentially harmful product, since many websites sell products that are not FDA approved and could be manufactured in other countries." The FDA first became aware of the problem in Rhode Island, but its probe turned up unapproved products in the two other states. The investigation is continuing, the agency said.

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